PolysacDB ID | 2601 |
Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Cryptococcus neoformans Serotype B (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The capsular polysaccharide has a linear α-(1-->3)-linked mannose backbone that is substituted with D-glucuronosyl acid groups. The mannose backbone is partially O-acetylated |
BCSDB Structure | 130477 |
Proposed functions | The capsular polysaccharide is an important virulence factor |
Antigenic Nature used to produce antibodies | Glycoconjugates |
Carrier Name | Sheep erythrocytes |
Conjugation Method | The capsular polysaccharide was adsorbed with 0.1 ml of packed sheep erythrocytes for 2 hours at room temperature |
Antibodies | Mab 339 |
Antibody type and class | N/A |
Assay System | ELISA and Immunodiffusion |
Cross-reactivity | This antibody cross-reacted with Serotype A,B,C and D serotypes |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | Used to differentiate various strains of all serotypes |
Curator ID | AA + AS |
Date of Curation | 15-07-2011
|
References | 2476401 |