PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2601
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeCryptococcus neoformans Serotype B   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe capsular polysaccharide has a linear α-(1-->3)-linked mannose backbone that is substituted with D-glucuronosyl acid groups. The mannose backbone is partially O-acetylated
BCSDB Structure130477
Proposed functionsThe capsular polysaccharide is an important virulence factor
Antigenic Nature used to produce antibodiesGlycoconjugates
Carrier NameSheep erythrocytes
Conjugation MethodThe capsular polysaccharide was adsorbed with 0.1 ml of packed sheep erythrocytes for 2 hours at room temperature
AntibodiesMab 339
Antibody type and classN/A
Assay SystemELISA and Immunodiffusion
Cross-reactivityThis antibody cross-reacted with Serotype A,B,C and D serotypes
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityUsed to differentiate various strains of all serotypes
Curator IDAA + AS
Date of Curation15-07-2011
References2476401


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