PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1526
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeKlebsiella pneumoniae O1:K2   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsIt has been shown to be an important virulence factor and potent antigen for the induction of immunoprotection
Antigenic Nature used to produce antibodiesLPS-associated proteins plus LPS
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 3A3
Antibody type and classIgM
Assay SystemELISA
Cross-reactivityThis Mab cross-reacted with K. pneumoniae R:K18, a rough strain. This Mab did not cross-react with LPS from Klebsiella strains of the 02, 03, and 04 serotypes nor LPS from E. coli 0111:B4
Proposed epitopesThis Mab recognized the LPS core
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation23-08-2010
ReferencesPMC313574


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