PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 2

Entry No. - 1   [TOP]
PolysacDB ID1063
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeEscherichia coli O157:H7   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 3b7
Antibody type and classIgM
Assay SystemELISA, immunoblotting, Fluorescent-antibody microscopy
Cross-reactivityThis antibody cross-reacted with group N Salmonella strains [(S. landau, S. soerenga, (S. urbana and S. godesberg]
Proposed epitopesCore antigen was proposed to be the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab provide a valuable tool for the rapid detection of E. coli O157
Curator IDAA + AS
Date of Curation19-01-2010
ReferencesPMC229650


Entry No. - 2   [TOP]
PolysacDB ID1264
Carbohydrate NameUnknown carbohydrate   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeCandida albicans Serotype A strain VW.32   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesUV-killed C. albicans strain VW.32 germ tubes
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 3b7
Antibody type and classIgM
Assay SystemELISA, Immunofluorescence
Cross-reactivityThis antibody cross-reacted with Candida albicans strain 3153A, strain 996B; Candida tropicalis strain Ct V. did not cross-react with other Candida species such as Candida glabrata, Candida albicans strain 995A and strain L; Candida pseudotropicalis, Candida krusei, Candida parapsilosis
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab may help in studying antigens that are involved in pathogenocity
Curator IDAA + AS
Date of Curation02-05-2010
References3058980


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036