PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1881
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis group A strain A1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureNeisseria meningitidis serogroup A capsular polysaccharide (CPS) is composed of a homopolymer of O-acetylated, α1-->6-linked ManNAc 1-phosphate
BCSDB Structure3136
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 4385G7
Antibody type and classIgG2b
Assay SystemELISA, immunodot assay, and ELISA inhibition assay
Cross-reactivityThis Mab was highly specific to A1 lipooligosaccharide but also cross-reacted with L8 lipooligosaccharide
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation21-11-2010
ReferencesPMC265440


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