PolysacDB ID | 1239 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Brucella abortus W99 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | O-polysaccharide consists of an unbranched linear homopolymer of 10 to 100 α-1,2-linked 4-formamido-4,6-dideoxy-D-mannose (N formylperosamine) residues. The O-polysaccharide is covalently linked to a core oligosaccharide
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Whole B. abortus W99 cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 4F9 |
Antibody type and class | IgG3 |
Assay System | ELISA |
Cross-reactivity | This antibody did not cross-react with S-LPSs of S. urbana, Vibrio cholerae and E. coli O:157, but cross-reacted with S-LPS of Y. enterocolitica O:9 along with Brucella A and M dominant strains. Reactivity was more towards A dominant strains |
Proposed epitopes | This Mab was directed against the C/Y epitope and did not consist of α1,2-linked D-Rha4NFo residues. This Mab did not bind purified O-polysaccharide |
IEDB Epitope | N/A |
Proposed Utility | This Mab helped in the epitope strucure elucidation |
Curator ID | AA + AS |
Date of Curation | 03-04-2010
|
References | PMC175246 |