|
|
Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us |
|
PolysacDB ID | 1327 |
Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Candida albicans B311 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 5B2 |
Antibody type and class | IgM |
Assay System | ELISA, immunofluorescence, crossed immunoelectrophoresis |
Cross-reactivity | This antibody cross-reacted with 5 strains of Candida albicans and also cross-reacted with Candida tropicalis and Candida stellatoidia but did not cross-react with T. glabrata and S. cerevisiae |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used to isolate surface components and determine the chemical structures that are responsible for the immunological differences. This Mab would facilitate the development of serological assays |
Curator ID | AA + AS |
Date of Curation | 13-06-2010 |
References | PMC259333 |
PolysacDB ID | 1342 |
Carbohydrate Name | Phosphopeptidomannan (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Candida albicans (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 5B2 |
Antibody type and class | N/A |
Assay System | ELISA, immunoblotting |
Cross-reactivity | N/A |
Proposed epitopes | The epitope consists of mannopyranosyl units bound through β(1-->2) linkages present both within the oligomannoside H pool and at the nonreducing end of some oligomannosides A |
IEDB Epitope | N/A |
Proposed Utility | This Mab helped in epitope elucidation of the mannans present on Candidial surfaces |
Curator ID | AA + AS |
Date of Curation | 23-06-2010 |
References | PMC257398 |
PolysacDB ID | 1344 |
Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Candida albicans (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Live C. albicans blastoconidia |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 5B2 |
Antibody type and class | IgM |
Assay System | Immunofluorescence and precipitin reactions |
Cross-reactivity | This Mab reacted with C. albicans, C. tropic alis, C. glabr-ata, and C. Giiillierrnondii |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab had the ability to agglutinate Candida species |
Curator ID | AA + AS |
Date of Curation | 24-06-2010 |
References | PMC260140 |
PolysacDB ID | 2180 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Salmonella typhimurium (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-α-D-Manp [branched to α-Abep-(1-->3)] -(1-->4)-α-L-Rhap-(1-->3)-α-D-Galp-(1- |
BCSDB Structure | 6380 |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 5B2 |
Antibody type and class | IgM |
Assay System | ELISA, immunoblotting, dot blot assay, immunoelectron microscopy |
Cross-reactivity | This Mab reacted with S. typhimurium (LPS O:1, 4, 5, and 12) while failing to recognize S. typhimurium var. copenhagen (LPS O:1, 4, and 12). It reacted equally with live and heat-attenuated Salmonella B serovars containing LPS O-5 antigen |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used to discriminate between S. typhimurium and S. typhimurium var. copenhagen |
Curator ID | AA + AS |
Date of Curation | 23-02-2011 |
References | PMC167767 |
Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |