PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1871
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis Serogroup B   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt consists of a homopolymer of α(2-->8)-linked sialic acid residues
BCSDB Structure7487
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesTonsillar B cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 5E1
Antibody type and classIgM
Assay SystemELISA
Cross-reactivityThis Mab reacts with E. coli K1 polysaccharide
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis antibody protected infant rats from bacteremia caused by Escherichia coli K1
Curator IDAA + AS
Date of Curation19-11-2010
References1988519


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036