PolysacDB ID | 2296 |
Carbohydrate Name | Core oligosaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Shigella spp. (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen consists of the following residues : -3)-β-D-Quip4NAc-(1-->2)-α-D-Manp [branched to α-L-Rhap-(1-->3)] -(1-->4)-β-D-Galp-(1-->3)-α-D-GlcpNAc-(1-
|
BCSDB Structure | N/A |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Heat killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 5E45D8 |
Antibody type and class | N/A |
Assay System | Indirect ELISA |
Cross-reactivity | This Mab was specific to S. flexneri |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab has potential importance in immunological detection of Shigella from unknown samples |
Curator ID | AA + AS |
Date of Curation | 24-03-2011
|
References | 11394534 |