| PolysacDB ID | 2460 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri 5b serotype (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-β-D-GlcpNAc-(1-->2)-α-L-Rhap [branched to α-D-Glcp-(1-->3)] -(1-->2)-α-L-Rhap [branched to α-D-Glcp-(1-->3)] -(1-->3)-α-L-Rhap-(1-
|
| BCSDB Structure | 108655 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 5b-B10 |
| Antibody type and class | IgG2a |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 5a LPS |
| Proposed epitopes | This Mab reacted with alkali-treated LPS |
| IEDB Epitope | 76660 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 23-05-2011
|
| References | 3531329 |