| PolysacDB ID | 1183 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 18530 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A
|
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | B. pertussis 18530 LPS |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 6-4-H6 |
| Antibody type and class | IgG3 |
| Assay System | ELISA |
| Cross-reactivity | This antibody cross-reacted with delipidated polysaccharide fragments (PS-1 and PS-2). did not react with LPS prepared from B. parapertussis and B. bronchiseptica. No cross-reactions were observed with strains of Branhamella catarrhalis, Neisseria meningitidis, Streptococcus miteor, Haemophilus influenza, or Legionella pneumophila |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab might be useful for the detection of soluble antigens and whole bacteria in clinical samples and for studies of the immunochemical structure of B. pertussis LPS. |
| Curator ID | AA + AS |
| Date of Curation | 27-02-2010
|
| References | PMC266249 |