PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1891
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis Serogroup B   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt consists of a homopolymer of α(2-->8)-linked sialic acid residues
BCSDB Structure7487
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 62
Antibody type and classIgM
Assay SystemCounter immunoelectrophoresis and slide agglutination tests
Cross-reactivityThis Mab was specific to group B polysaccharide and did not cross-react with Haemophilus influenza and Streptococcus pneumoniae
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used in culture identification.
Curator IDAA + AS
Date of Curation23-11-2010
ReferencesPMC269298


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