PolysacDB ID | 2070 |
Carbohydrate Name | Inner core oligosaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Pseudomonas aeruginosa (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The core region of LPS is divided into the outer core and inner core. The inner core region consists of 2-keto-3-deoxyoctonic acid (KDO), heptose, phosphate, and probably ethanolamine. The outer core region commonly contains D-glucose, L-rhamnose, D-galactosamine, and L-alanine. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Core-LPS coated Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 7-4 |
Antibody type and class | N/A |
Assay System | ELISA and immunoblotting |
Cross-reactivity | "This Mab cross-reacted with all 20 P. aeruginosa serotypes as well as with other Pseudomonas species namely, P. acidovorans, P. chlororaphis, P. syringae, P.putida, P. aureofaciens, and P. stutzeri. MAb 7-4 did not react with other non-Pseudomonas gram negative organisms" |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 07-01-2011
|
References | PMC197099 |