PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1861
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis group C strain C11   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt consists of a homopolymer of α(2-->9)-linked sialic acid residues
BCSDB StructureN/A
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 78.2
Antibody type and classIgG2b
Assay SystemFluorescence ELISA, Ouchterlony precipitation, Bacterial agglutination assay, Bactericidal assay
Cross-reactivityThis Mab was highly specific to group C polysaccharide and did not react with K1 polysaccharide
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had bactericidal activity
Curator IDAA + AS
Date of Curation18-11-2010
References3143763


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036