PolysacDB ID | 1798 |
Carbohydrate Name | N-propionylated α(2-->8)-linked sialooligosaccharides (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Neisseria meningitidis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N-propionylated α(2-->8)-linked sialooligosaccharides
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Glycoconjugates |
Carrier Name | Tetanus toxoid |
Conjugation Method | The oligosaccharide was activated using NaIO4 at 4°C for 60 min and combined with monomeric tetanus toxoid in sodium phosphate buffer containing NaBH3CN and heated at 37°C for 5 days |
Antibodies | Mab 7C11 |
Antibody type and class | IgG1 |
Assay System | ELISA, bactericidal assays |
Cross-reactivity | N/A |
Proposed epitopes | The epitope was located on short internal fragments of the polysaccharide |
IEDB Epitope | N/A |
Proposed Utility | This Mab would help in the elucidation of the capsular polysaccharide structure |
Curator ID | AA + AS |
Date of Curation | 03-11-2010
|
References | PMC2196336 |