PolysacDB ID | 1654 |
Carbohydrate Name | Lipoarabinomannan (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Mycobacterium leprae (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Lipoarabinomannan is a complex carbohydrate containing arabinose, mannose, glycerol, and myo-inositol 1-phosphate, in addition to lactate, succinate, palmitate, and 10 methyloctadecanoate
|
BCSDB Structure | 127448 |
Proposed functions | T cell proliferation and to interfere with gamma interferon-mediated activation of macrophages |
Antigenic Nature used to produce antibodies | A combination of M. leprae 30KS and 1OKP |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab A12B |
Antibody type and class | IgG1 |
Assay System | ELISA, immunoblotting |
Cross-reactivity | This Mab was specific for M. leprae LAM |
Proposed epitopes | α(1-->5)-linked arabinofuranosyl residues seemed to be a part of the epitope |
IEDB Epitope | N/A |
Proposed Utility | This Mab would help in the structure elucidation of lipoarabinomanna |
Curator ID | AA + AS |
Date of Curation | 30-09-2010
|
References | PMC259992 |