PolysacDB ID | 2420 |
Carbohydrate Name | Streptococcal A carbohydrate (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Streptococcus Group A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A
|
BCSDB Structure | N/A |
Proposed functions | This Carbohydrate is highly immunodominant |
Antigenic Nature used to produce antibodies | Sera of humans having IgM myeloma |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab AC179 |
Antibody type and class | IgM |
Assay System | Solid-phase enzyme-linked immunoassay, Streptococcal agglutination assay |
Cross-reactivity | ACI79 was most active in agglutinating A variant (Av) and group C streptococci |
Proposed epitopes | AC179 is directed to α-linked rhamnose oligosaccharides |
IEDB Epitope | 76687 |
Proposed Utility | AC179 induced complement activation in the presence of the carbohydrate |
Curator ID | AA + AS |
Date of Curation | 07-05-2011
|
References | 2579417 |