PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2419
Carbohydrate NameStreptococcal A carbohydrate   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeStreptococcus Group A   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsThis Carbohydrate is highly immunodominant
Antigenic Nature used to produce antibodiesSera of humans having IgM myeloma
Carrier NameNil
Conjugation MethodNil
AntibodiesMab AC8
Antibody type and classIgM
Assay SystemSolid-phase enzyme-linked immunoassay, Streptococcal agglutination assay
Cross-reactivityAC8 agglutinated preferentially group A streptococci
Proposed epitopesAC8 appears to be specific for N-acetly-D-glucosamine (GlcNAc) side chains β(1-->2)-linked to rhamnose
IEDB Epitope76687
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation07-05-2011
References2579417


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036