| PolysacDB ID | 1641 |
| Carbohydrate Name | Phenolic glycolipid antigen (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe | Mycobacterium leprae (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It consisting of terminal 3,6-di-O-methyl glucose linked β1-->4 to 2,3-di-O-methyl rhamnose, which in turn is linked α1-->2 to 3-O-methyl rhamnose
|
| BCSDB Structure | 114263 |
| Proposed functions | It has been proposed to protect pathogenic mycobacteria such as Mycobacterium lepraemurium from the host bactericidal activities in phagocytic cells |
| Antigenic Nature used to produce antibodies | Partially purified phenolic glycolipid from M. leprae |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab B9D |
| Antibody type and class | IgM |
| Assay System | ELISA, TLC autoradiography and immunofluorescence |
| Cross-reactivity | This Mab cross-reacted with M. kansasii phenolic glycolipid and cross-reacted with whole cells of 20 mycobacterial strains |
| Proposed epitopes | Terminal 3,6-di-O-methyl glucose residues were proposed to be a part of the epitope |
| IEDB Epitope | 76895 |
| Proposed Utility | This Mab may provide more information on the structure of phenolic glycolipid of M. leprae and the localization of this antigen can be performed within infected lesions by immunofluorescence |
| Curator ID | AA + AS |
| Date of Curation | 26-09-2010
|
| References | PMC263407 |