PolysacDB ID | 1864 |
Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Neisseria meningitidis Serogroup B (NCBI Taxonomy) (Drugpedia) |
Basic Structure | It consists of a homopolymer of α(2-->8)-linked sialic acid residues
|
BCSDB Structure | 7487 |
Proposed functions | It is an important virulence factor |
Antigenic Nature used to produce antibodies | Infected patient |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab BES |
Antibody type and class | IgM |
Assay System | ELISA, Rat protection assay |
Cross-reactivity | This Mab cross-reacts with E. coli K1 polysaccharide but does not react with E. coli K92, group A and group C polysaccharides of Neisseria meningitidis. This Mab also reacts with N-propionylated group B polysaccharide |
Proposed epitopes | The epitope consisted of α2-8 linked N-acetylneuraminic acid acid residues |
IEDB Epitope | N/A |
Proposed Utility | This antibody protected infant rats from bacteremia caused by Escherichia coli K1 |
Curator ID | AA + AS |
Date of Curation | 18-11-2010
|
References | PMC173242 |