PolysacDB ID | 1160 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Bacteroides fragilis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The polysaccharide part of the LPS mainly consists of two fractions : PSI : β-D-Galp(1-->6)β-D-Galp(1-->6)β-D-Galp(1-->6)Residue1-α-D-Glcp [branched to Residue no. 2](1-->2)α-L-Rhap and PSII : β-D-Galp(1-->4)α-D-Glcp [Branched to β-D-Galp(1-->6)](1-->2)α-L-Rhap
|
BCSDB Structure | 122912 |
Proposed functions | LPS polysaccharide of B. gingivalis may represent a virulence factor |
Antigenic Nature used to produce antibodies | Outer membrane extract of B. fragilis 23475 |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab BF5 |
Antibody type and class | N/A |
Assay System | Enzyme Immunoassay, Inhibition assay, Immunoblotting |
Cross-reactivity | This antibody cross-reacted with 68 strains of B. fragilis, 5 strains of B.thetaiotaomicron, 2 strains of B. ovatus. Also partially cross-reacted with and one P. aeruiginosa strain |
Proposed epitopes | N/A
|
IEDB Epitope | N/A |
Proposed Utility | Using this Mab LPS can be easily detected in bacterial antigen preparations and clinical samples. |
Curator ID | AA + AS |
Date of Curation | 22-02-2010
|
References | PMC271363 |