| PolysacDB ID | 1247 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Brucella melitensis 16M (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | O-polysaccharide is a homopolymer of 4,6-dideoxy-4-formamidoct-D-mannopyranose residues
|
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | B.melitensis 16M formaldehyde-killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BM3-7 |
| Antibody type and class | IgG2b |
| Assay System | ELISA, immunodiffusion and competitive inhibition assay |
| Cross-reactivity | This antibody was specific to B. melitiensis and did not cross-reac with O-polysaccharide of B. abortus and Yersinia enterocolitica O:9 polysaccharide |
| Proposed epitopes | This Mab reacted only with M antigen. The crucial element of the M epitope is a disaccharide, α-D-Rha4NFo(1-->3)α-D Rha4NFo, that requires adjacent α1,2-linked residues for full activity. The common epitope of A and M antigens is a linear α1,2-linked tri or tetrasaccharide |
| IEDB Epitope | 76740 |
| Proposed Utility | This Mab can be used as a use as standard Brucella typing or detection reagents |
| Curator ID | AA + AS |
| Date of Curation | 07-04-2010
|
| References | PMC313534 |