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PolysacDB ID | 1265 |
Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Candida albicans (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab C6 |
Antibody type and class | IgM |
Assay System | ELISA, immunoelecton microscopy and agglutination tests |
Cross-reactivity | This antibody cross-reacted with 30 strains of Candida albicans strains, 2 strains of Candida tropicalis but did not cross-react with Candida paratropicalis, Candida parapsilosis, T. glabrata and S. cerevisae. |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab had a agglutinating activity against Candida albicans |
Curator ID | AA + AS |
Date of Curation | 02-05-2010 |
References | 3280163 |
PolysacDB ID | 1334 |
Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Candida albicans 3153A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Cell wall extract of wild-type Candida albicans 3153A |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab C6 |
Antibody type and class | N/A |
Assay System | ELISA, Immunofluorescence and immunoblotting |
Cross-reactivity | This antibody cross-reacted with strain 62, B, 4C, 24, 37, 53, and 22 but did not react with 4A, 16, 28 and 47 strains |
Proposed epitopes | The epitope is supposed to contain high concentrations of glucose and mannose and is present in the acid-labile oligomannosaccharides. |
IEDB Epitope | N/A |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 18-06-2010 |
References | PMC281022 |
PolysacDB ID | 1341 |
Carbohydrate Name | Phosphopeptidomannan (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Candida albicans (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab C6 |
Antibody type and class | N/A |
Assay System | ELISA, immunoblotting |
Cross-reactivity | N/A |
Proposed epitopes | The epitope consiosts of mannosyl residues from mannobiose to mannoheptaose are bound through β(1-->2) linkage |
IEDB Epitope | N/A |
Proposed Utility | This Mab helped in epitope elucidation of the mannans present on Candidial surfaces |
Curator ID | AA + AS |
Date of Curation | 22-06-2010 |
References | PMC257398 |
PolysacDB ID | 2553 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Vibrio cholerae 01 Inaba 569B strain (NCBI Taxonomy) (Drugpedia) |
Basic Structure | It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
BCSDB Structure | N/A |
Proposed functions | V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera |
Antigenic Nature used to produce antibodies | Purified LPS |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab C6 |
Antibody type and class | IgG3 |
Assay System | Enzyme-linked immunosorbent assay inhibition experiments |
Cross-reactivity | This Mab was specific to Inaba 35 and 569B LPS only |
Proposed epitopes | This Mab was specific to C antigen |
IEDB Epitope | N/A |
Proposed Utility | This Mab had a good agglutinating capacity when tested against V. cholerae 0:1 strains |
Curator ID | AA + AS |
Date of Curation | 25-06-2011 |
References | PMC270838 |
Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |