PolysacDB ID | 2182 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Serogroup C1 (0:6,7) Salmonella (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-β-D-Manp-(1-->2)-α-D-Manp [branched to α-D-Glcp-(1-->3)] -(1-->2)-α-D-Manp-(1-->2)-α-D-Manp-(1-->3)-β-D-GlcpNAc-(1-
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BCSDB Structure | N/A |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab Cl-1 |
Antibody type and class | IgG3 |
Assay System | ELISA, slide agglutination test |
Cross-reactivity | This Mab reacted strongly with all strains of serogroup C1 Salmonella that have either O:6(1),7, O:6(2),7, or O:6(1,2),7 antigens and also reacted with the phage-14 lysogenized C1 strains that bear the phage-modified O antigen (O:6,7----O:6,7,14) |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used for the diagnosis of serogroup C1 salmonella |
Curator ID | AA + AS |
Date of Curation | 24-02-2011
|
References | 1374696 |