PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 2

Entry No. - 1   [TOP]
PolysacDB ID1381
Carbohydrate NameGP900 antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeCryptosporidium parvum   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesSupernatant from sonicated Oocysts
Carrier NameNil
Conjugation MethodNil
AntibodiesMab E6
Antibody type and classN/A
Assay SystemImmunoprecipitation and immunofluorescence
Cross-reactivityN/A
Proposed epitopesN-linked carbohydrates seem to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab is a potential target for passive immunotherapy against cryptosporidiosis
Curator IDAA + AS
Date of Curation03-07-2010
ReferencesPMC258288


Entry No. - 2   [TOP]
PolysacDB ID2586
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeRhizobium leguminosarum biovar trifolii strain 162X95   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsStructural modifications of Rhizobium LPS may play an important role in the adaptation of endosymbiotic rhizobia to the surrounding microenvironment
Antigenic Nature used to produce antibodiesHeat treated cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab E6
Antibody type and classIgG3
Assay SystemCompetitive enzyme-linked immunosorbent assay, ELISA, immunoblotting
Cross-reactivityThis MAb to the O antigen of R. trifolii 162X95 has been shown to be specific for six strains of R. trifolii only
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for immunodetection of R. trifolii
Curator IDAA + AS
Date of Curation08-07-2011
ReferencesPMC184596


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