PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2004
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-2
Antibody type and classIgG2b
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation15-12-2010
References3081727


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