PolysacDB ID | 2637 |
Carbohydrate Name | Glucurunoxylomannan (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Cryptococcus neoformans Serotype B (NCBI Taxonomy) (Drugpedia) |
Basic Structure | A linear α(1-->3)- linked mannan backbone singly substituted with non-reducing β(1-->2) xylose and β(1-->2) glucuronic acid side branches ; O-acetyl groups are present at C-6 of the mannosyl residues
|
BCSDB Structure | 9354 |
Proposed functions | Antiphagocytic ; an important virulence factor |
Antigenic Nature used to produce antibodies | Glycoconjugates |
Carrier Name | Sheep erythrocytes |
Conjugation Method | The capsular polysaccharide was adsorbed with 0.1 ml of packed sheep erythrocytes for 2 hours at room temperature |
Antibodies | Mab F10F5 |
Antibody type and class | IgG1 |
Assay System | ELISA |
Cross-reactivity | This antibody cross-reacted with Serotypes A and B |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This antibody was used in the elucidation of the probable epitopes present in glucurunoxylomannan |
Curator ID | AA + AS |
Date of Curation | 28-07-2011
|
References | 12965925 |