PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2054
Carbohydrate NameCell surface polysaccharide alginate   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobePseudomonas aeruginosa   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesPurified alginate
Carrier NameNil
Conjugation MethodNil
AntibodiesMab F431
Antibody type and classIgG1
Assay SystemELISA and protection assays
Cross-reactivityN/A
Proposed epitopesIntact carboxylate groups on the C6 carbon of the mannuronic acid residues
IEDB EpitopeN/A
Proposed UtilityThis Mab was found to promote phagocytic killing of both mucoid and nonmucoid strains as well as conferred protection against both types of strains in a mouse model of acute pneumonia
Curator IDAA + AS
Date of Curation30-12-2010
References15494518


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036