| PolysacDB ID | 1361 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Chlamydia trachomatis serotype F (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The LPS is composed of the pentasaccharide bisphosphate αKdo-(2-8)-αKdo-(2-->4)-αKdo-(2-6)-βGlcN-4P-(1-->6) αGlcN-1P (Kdo is 3-deoxy-α-d-manno-oct-2-ulosonic acid)
|
| BCSDB Structure | N/A |
| Proposed functions | LPS is most unusual constituents of outer membrane. It plays important role in host defence avoidance. LPS contributes to the negative charge of the bacterial surface. Lipid A is often toxic and act as endotoxin |
| Antigenic Nature used to produce antibodies | Elementary bodies of Chlamydia trachomatis serotype F |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab F6-A4 |
| Antibody type and class | IgG3 |
| Assay System | IFT assay, ELISA |
| Cross-reactivity | This antibody cross-reacted with Salmonella Minnesota LPS and Chlamydia psittaci |
| Proposed epitopes | The epitope cosisted of a trisaccharide of a-3-deoxy-D-manno-2-octulosonic acid (KDO) |
| IEDB Epitope | 76828 |
| Proposed Utility | This Mab can be used in the epitope characterization of Chlamydial LPS |
| Curator ID | AA + AS |
| Date of Curation | 28-06-2010
|
| References | PMC258430 |