PolysacDB ID | 1360 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Chlamydia trachomatis serotype G (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS is composed of the pentasaccharide bisphosphate αKdo-(2-8)-αKdo-(2-->4)-αKdo-(2-6)-βGlcN-4P-(1-->6) αGlcN-1P (Kdo is 3-deoxy-α-d-manno-oct-2-ulosonic acid)
|
BCSDB Structure | N/A |
Proposed functions | LPS is most unusual constituents of outer membrane. It plays important role in host defence avoidance. LPS contributes to the negative charge of the bacterial surface. Lipid A is often toxic and act as endotoxin |
Antigenic Nature used to produce antibodies | Elementary bodies of Chlamydia trachomatis serotype G |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab G2-B3 |
Antibody type and class | IgG2b |
Assay System | IFT assay, ELISA |
Cross-reactivity | This antibody cross-reacted with Salmonella Minnesota LPS and Chlamydia psittaci |
Proposed epitopes | The epitope cosisted of a trisaccharide of a-3-deoxy-D-manno-2-octulosonic acid (KDO) |
IEDB Epitope | 76828 |
Proposed Utility | This Mab can be used in the epitope characterization of Chlamydial LPS |
Curator ID | AA + AS |
Date of Curation | 27-06-2010
|
References | PMC258430 |