| PolysacDB ID | 1163 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B
|
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | Whole cells of Bordetella Pertusis |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab HBp2 |
| Antibody type and class | IgM |
| Assay System | Dot enzyme Immunoassay, Immunoblotting |
| Cross-reactivity | This antibody reacted with all B. pertusis strains. also cross-reacted with a clinical isolate of B. bronchiseptica. No cross-reaction was observed against B. parapertussis and other gram-negative species |
| Proposed epitopes | N/A
|
| IEDB Epitope | N/A |
| Proposed Utility | Mab HBp2 showed high lytic capability against B. pertussis |
| Curator ID | AA + AS |
| Date of Curation | 23-02-2010
|
| References | 1721552 |