| PolysacDB ID | 1832 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Escherichia coli K1 strain (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It consists of a homopolymer of α(2-->8)-linked sialic acid residues
|
| BCSDB Structure | 6824 |
| Proposed functions | It is an important virulence factor |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab HmenB1 |
| Antibody type and class | IgM |
| Assay System | ELISA, flow cytometry and bactericidal assay |
| Cross-reactivity | This Mab cross-reacted with Neisseria meningitidis Group B capsular polysaccharide and EV36 which is an E. coli K-12 strain possessing the genes for K1 capsular polysaccharide production and expresses non-acetylated α (2-->8) polysaccharide just like Neisseria meningitidis group B capsular polysaccharide. This Mab also reacted on the surface of human neuroblastoma cell line, CHP-134 |
| Proposed epitopes | α(2-->8)-linked units of N-acetylneuraminic acid residues seemed to be the part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 11-11-2010
|
| References | PMC98292 |