PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1995
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeStreptococcus pneumoniae serotype 6B   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe capsular polysaccharide consists of the following residues : -2)-α-D-Galp-(1-->3)-α-D-Glcp-(1-->3)-α-L-Rhap-(1-->4)-D-Rib-ol-(5-P-
BCSDB Structure5205
Proposed functionsN/A
Antigenic Nature used to produce antibodiesGlycoconjugates
Carrier NameDiphtheria toxin mutant (CRM197)
Conjugation MethodN/A
AntibodiesMab Hyp6BM17
Antibody type and classIgM
Assay SystemSandwich ELISA, opsonization assays
Cross-reactivityThis Mab cross-reacted with strain 6A
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had opsonophagocytic activity
Curator IDAA + AS
Date of Curation13-12-2010
ReferencesPMC97888


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