| PolysacDB ID | 1452 |
| Carbohydrate Name | FVP2 polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Flammulina velutipes (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of an α-(1-->4)-D-glucan, branching with a single α-D-glucan at the C-6 position to every seven residues along the main chain
|
| BCSDB Structure | N/A |
| Proposed functions | FVP2 can enhance the livability of primary culture of mouse hepatocytes in vitro and decrease the release of the alanine aminotransferase (ALT) as well as apoptosis of hepatocytes after the carbon tetrachloride (CCl4) intoxication. Furthermore, FVP2 has the capability of suppressing the growth of hepatoma 22 cells and sarcoma 180 cells (S180), extending the survival time of L615 leukemia mice, and promoting the lymphocyte transformation rate, natural killer cell activity, and the interleukin-2 production index in normal and tumor-bearing (S180) mice |
| Antigenic Nature used to produce antibodies | Glycoconjugates |
| Carrier Name | Bovine serum albumin |
| Conjugation Method | The FVP2 polysaccharide was conjugated to BSA using 1-cyano-4-dimethyl-aminopyridinium tetrafluoroborate (CDAP) treatment |
| Antibodies | Mab I6D |
| Antibody type and class | IgM |
| Assay System | Indirect ELISA, Double Immunodiffusion |
| Cross-reactivity | N/A |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab provides a potentially useful tool for further study in the development of a novel and efficient immunoassay to detect FVP2 in biological specimens |
| Curator ID | AA + AS |
| Date of Curation | 21-07-2010
|
| References | 19108616 |