PolysacDB ID | 2395 |
Carbohydrate Name | 125 Kda antigen (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Streptococcus mutans OMZ175 (serotype f) (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Cell wall extracted antigens |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab LOSM3 |
Antibody type and class | IgM |
Assay System | Western blotting and immunoprecipitation techniques, enzyme-linked immunosorbent assay (ELISA), and competitive ELISA |
Cross-reactivity | Monoclonal antibody LOSM1 showed a quite identical reactivity with WEA from S. mutans serotypes f and b, reduced activity against WEA from serotypes c, e, and a, and weak binding to serotypes d and g |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | Using this monoclonal antibody, it has been demonstrated that cross-reactivity and conservation of the specific epitopes among the various S. mutans serotypes. These Mab should be useful in studying the streptococcal surface moities |
Curator ID | AA + AS |
Date of Curation | 29-04-2011
|
References | PMC262021 |