| PolysacDB ID | 1259 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Campylobacter fetus 554 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)
|
| BCSDB Structure | N/A |
| Proposed functions | The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme |
| Antigenic Nature used to produce antibodies | A mixture (1:1) of C. fetus 553 and 554 formalin-killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab M1177 |
| Antibody type and class | IgG1 |
| Assay System | Indirect ELISA, immunoblotting, |
| Cross-reactivity | This antibody was specific to O antigen of C. fetus 554 and did not cross-react with C. fetus 553 |
| Proposed epitopes | Acetylated groups seem to be an important part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to serotype C. fetus strains |
| Curator ID | AA + AS |
| Date of Curation | 28-04-2010
|
| References | PMC98852 |