PolysacDB ID | 1261 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Campylobacter fetus 554 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)
|
BCSDB Structure | N/A |
Proposed functions | The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme |
Antigenic Nature used to produce antibodies | A mixture (1:1) of C. fetus 553 and 554 formalin-killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab M1183 |
Antibody type and class | IgG1 |
Assay System | Indirect ELISA, immunoblotting, |
Cross-reactivity | This antibody was specific to O antigen of C. fetus 553 and did not cross-react with C. fetus 554 |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used to serotype C. fetus strains |
Curator ID | AA + AS |
Date of Curation | 02-05-2010
|
References | PMC98852 |