PolysacDB ID | 2299 |
Carbohydrate Name | Core oligosaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Campylobacter fetus (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)
|
BCSDB Structure | N/A |
Proposed functions | The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab M1357 |
Antibody type and class | N/A |
Assay System | ELISA and immunoblotting |
Cross-reactivity | This Mab was highly specific tp C. fetus strains and reacted with serotype A and B strains |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | Due to its high specificity, this Mab is potentially useful as immunodiagnostic reagent for detection, identification and characterization of C. fetus |
Curator ID | AA + AS |
Date of Curation | 25-03-2011
|
References | 12079745 |