PolysacDB ID | 2231 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Salmonella typhimurium SL 1102 [Re] (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain
|
BCSDB Structure | N/A |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Heat killed bacteria |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MAEC7 |
Antibody type and class | IgG2b |
Assay System | Enzyme immunoassay |
Cross-reactivity | This Mab cross-reacted with Rd2 LPS |
Proposed epitopes | 3-deoxy-D-mannooctulosonic acid [KDO] residues at the terminal non-reducing ends seemed to be the part of the epitope. The particular epitope was proposed to be α-Kdo[2-->4] Kdo |
IEDB Epitope | N/A |
Proposed Utility | This Mab would help elucidate the Kdo LPS domain structure |
Curator ID | AA + AS |
Date of Curation | 15-03-2011
|
References | 2033255 |