PolysacDB ID | 1459 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Haemophilus ducreyi (NCBI Taxonomy) (Drugpedia) |
Basic Structure | It consist of an oligosaccharide core ketosidically linked via a 3-deoxy-D-manno-octulosonic acid (Kdo) residue to the lipid A region. The oligosaccharide core characteristic of these bacteria has been divided into two regions: (i) an inner core, consisting of three L-glycero-D-manno-heptose (Hep) residues and one phosphorylated Kdo residue, and (ii) an outer core, with one or more heterogeneous oligosaccharide branches containing mainly galactose (Gal) and glucose (Glc) residues
|
BCSDB Structure | 1605 |
Proposed functions | LPS plays an important role in the infection process |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MAHD7 |
Antibody type and class | IgM |
Assay System | ELISA and immunoblotting |
Cross-reactivity | It reacts with all H. ducreyi strains |
Proposed epitopes | MAb MAHD7 recognizes the common conserved inner core region of the LOS |
IEDB Epitope | N/A |
Proposed Utility | This Mab would aid in the classification of H. ducreyi for epidemiological purposes |
Curator ID | AA + AS |
Date of Curation | 23-07-2010
|
References | PMC175445 |