| PolysacDB ID | 1457 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Haemophilus influenzae RM.7004 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It consists of an oligosaccharide linked via a 3-deoxy-D-manno-octulosonic acid (Kdo) residue to a lipid A region. The core is often divided into two regions: an inner core consisting of a heptose (Hep) and a Kdo residue and an outer core containing galactose (Gal) and glucose (Glc)
|
| BCSDB Structure | N/A |
| Proposed functions | LPS plays an important role in the infection process |
| Antigenic Nature used to produce antibodies | Azide-killed H. influenzae RM.7004 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MAHI 3 |
| Antibody type and class | IgG2b |
| Assay System | Enzyme immunoassay, colony dot immunoblotting, and immunoblotting |
| Cross-reactivity | MAHI 3 bound to all H. influenzae, all other human Haemophilus spp., all Bordetella pertussis and Bordetella parapertussis, and all Aeromonas spp. tested but not to any Neisseria or Moraxella catarrhalis strains |
| Proposed epitopes | The structural element recognized by MAHI 3 is Hepα1-->2Hepα1-->3Hepα1-->Kdo together with part of lipid A, including the phosphate |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help to detect the organism in environmental samples and clinical specimens |
| Curator ID | AA + AS |
| Date of Curation | 23-07-2010
|
| References | PMC173510 |