PolysacDB ID | 2216 |
Carbohydrate Name | Core oligosaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Salmonella choleraesuis SN57 [Ra] (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain
|
BCSDB Structure | N/A |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MASC1-MM3 |
Antibody type and class | IgM |
Assay System | Enzyme immunoassay, immunoblotting |
Cross-reactivity | This Mab cross-reacted with with six different Salmonella core chemotypes S, Ra, Rb1, Rb2, Rb3, Rc and Rd1, the R2 core of Escherichia coli and a variety of smooth LPS |
Proposed epitopes | The terminal disaccharide L-α-D-Hep1-->7-L-α-D-Hep1-O-me seemed to be the immunodominant epitope |
IEDB Epitope | N/A |
Proposed Utility | This Mab would help elucidate the LPS core domain structure |
Curator ID | AA + AS |
Date of Curation | 08-03-2011
|
References | 1383323 |