| PolysacDB ID | 2332 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Chemically, the O-antigen is a polysaccharide chain of variable length, built up by repetitive sequences of tetra- to hexasaccharides. It consists of a basic tetrasaccharide repeating unit consisting of three rhamnoses and one N-acetylglucosamine was common to all S. flexneri strains (except serotype 17): -2)-α-L-Rhap-(1-->2)-α-L-Rhap-(1-->3)-α-L-Rhap-(1-->3)-β-D-GlcpNAc-(1-->
|
| BCSDB Structure | 3707 |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Heat killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MASF 6 |
| Antibody type and class | IgG |
| Assay System | ELISA, slide agglutination |
| Cross-reactivity | This Mab cross-reacted with serotype 1b, 3a, 3b and 3c |
| Proposed epitopes | N/A |
| IEDB Epitope | 76815 |
| Proposed Utility | This Mab can be useful for antigen detection in stool samples. Furthermore, use of the panel of monoclonal antibodies made it possible to identify two strains (Y394 and Y400) as putative members of a new provisional serotype of S. flexneri |
| Curator ID | AA + AS |
| Date of Curation | 04-04-2011
|
| References | PMC267520 |