PolysacDB ID | 2318 |
Carbohydrate Name | Core oligosaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Shigella flexneri serotype 1b (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The core is a single sequence of heptoses and hexoses
|
BCSDB Structure | N/A |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Heat killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MASF R3 core-1 |
Antibody type and class | IgG2a |
Assay System | Immunoblotting, enzyme-linked immunosorbent assay (ELISA), hemagglutination, and coagglutination |
Cross-reactivity | The core-specific antibodies were shown to be specific for the Escherichia coli R3 core, which all S. flexneri LPSs were found to have, except for S. flexneri serotype 6 LPS |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used for detection and identification of shigella flexneri species |
Curator ID | AA + AS |
Date of Curation | 31-03-2011
|
References | 2424839 |