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| PolysacDB ID | 2218 |
| Carbohydrate Name | Core oligosaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Salmonella minnesota Re chemotype 595 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The core oligosaccharide part consists of the following residues : α-Kdop-(2-8)-α-Kdop-(2-->4)-Kdo |
| BCSDB Structure | 147530 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MASM2 |
| Antibody type and class | IgG2b |
| Assay System | Enzyme immunoassay, immunoblotting |
| Cross-reactivity | This Mab was specific to Re chemotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help elucidate the LPS core domain structure |
| Curator ID | AA + AS |
| Date of Curation | 08-03-2011 |
| References | 1383323 |
| PolysacDB ID | 2228 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Salmonella minnesota Re chemotype 595 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The core oligosaccharide part consists of the following residues : α-Kdop-(2-8)-α-Kdop-(2-->4)-Kdo |
| BCSDB Structure | 147530 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Heat killed bacteria |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MASM2 |
| Antibody type and class | IgG2b |
| Assay System | Enzyme immunoassay, ELISA |
| Cross-reactivity | This Mab cross-reacted with Salmoneela typhimurium SL1102 Re chemotype LPS |
| Proposed epitopes | 3-deoxy-D-mannooctulosonic acid [KDO] residues at the terminal non-reducing ends seemed to be the part of the epitope. The particular epitope was proposed to be α-Kdo [2-->4] α-Kdo [2-->6] β-D-GlcN [1-->6] α-D-GlcN [1-PO3] tetrasaccharide |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help elucidate the Kdo LPS domain structure |
| Curator ID | AA + AS |
| Date of Curation | 13-03-2011 |
| References | 2033255 |
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Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |