| PolysacDB ID | 2211 |
| Carbohydrate Name | Capsular Vi polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Salmonella typhi (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The salmonella Vi Capsular polysaccharide is a linear homopolymer of α[1-->4]-O-acetyl-N-acetyl-galactosaminuronic acid
|
| BCSDB Structure | 3149 |
| Proposed functions | It is an important virulence factor. The Vi capsule shields the bacteria against phagocytosis by its surface negative charge properties and by covering cell-envelope components sensitive to serum opsonins |
| Antigenic Nature used to produce antibodies | Heat killed bacteria and purified Vi polysaccharide |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MATy-V7 |
| Antibody type and class | IgM |
| Assay System | Inhibition enzyme immunoassay |
| Cross-reactivity | This Mab was specific to Vi antigen |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was shown to be a useful serotyping agent by correct identification in slide agglutination tests of 32 clinical isolates of all the S. typhi and other serogroup D salmonellae among a total of 140 bacterial isolates representing eight different Enterobacteriaceae genera tested |
| Curator ID | AA + AS |
| Date of Curation | 04-03-2011
|
| References | 1426999 |