PolysacDB ID | 2215 |
Carbohydrate Name | Capsular Vi polysaccharide (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Salmonella typhi (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The salmonella Vi Capsular polysaccharide is a linear homopolymer of α[1-->4]-O-acetyl-N-acetyl-galactosaminuronic acid
|
BCSDB Structure | 3149 |
Proposed functions | It is an important virulence factor. The Vi capsule shields the bacteria against phagocytosis by its surface negative charge properties and by covering cell-envelope components sensitive to serum opsonins |
Antigenic Nature used to produce antibodies | Heat killed bacteria and purified Vi polysaccharide |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MATy-V9 |
Antibody type and class | IgM |
Assay System | Inhibition enzyme immunoassay |
Cross-reactivity | This Mab was specific to Vi antigen |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab was shown to be a useful serotyping agent by correct identification in slide agglutination tests of 32 clinical isolates of all the S. typhi and other serogroup D salmonellae among a total of 140 bacterial isolates representing eight different Enterobacteriaceae genera tested |
Curator ID | AA + AS |
Date of Curation | 08-03-2011
|
References | 1426999 |