PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1712
Carbohydrate NameUnknown carbohydrate   (Drugpedia)
Carbohydrate ClassGlycolipid
MicrobeMycobacterium leprae   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesSupernatant fraction of sonicated M. leprae
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ML09
Antibody type and classIgG3
Assay SystemRadioimmunoassays, immunoblotting
Cross-reactivityThis Mab was highly cross-reactive and cross-reacted with all ten mycobacterial strains studied except for M. scrofulaceum, M. neoaurum and M. lepraemurium
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab may represent a novel valuable diagnostic reagent as well as tool for the purification of antigens which could be explored towards prophylactic or therapeutic immunization against leprosy.
Curator IDAA + AS
Date of Curation13-10-2010
ReferencesPMC1536026


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