PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1522
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeKlebsiella pneumoniae   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsCPS have been shown to be important virulence factors and potent Ag for the induction of immunoprotection
Antigenic Nature used to produce antibodiesA 24-valent K. pneumoniae CPS vaccine containing the serotypes 2, 3, 5, 9, 10, 15, 16. 17, 18, 21, 22, 25, 28. 30, 35, 43, 52, 53, 55, 60, 61, 62, 63, and 64
Carrier NameNil
Conjugation MethodNil
AntibodiesMab MT72 H99
Antibody type and classIgM
Assay SystemELISA and immunofluorescence
Cross-reactivityThis Mab recognised K5, K6, K7, K10, K20, K49, K61, K62, K64 and K74 strains
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab may prove valuable as diagnostic tools and that an immunotherapy is feasible
Curator IDAA + AS
Date of Curation21-08-2010
References2016541


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