PolysacDB ID | 2539 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia) |
Basic Structure | It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
BCSDB Structure | N/A |
Proposed functions | V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera |
Antigenic Nature used to produce antibodies | Killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab OF7 |
Antibody type and class | IgM |
Assay System | Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis |
Cross-reactivity | This Mab reacted only with Ogawa-type V. cholerae |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab agglutinated both live and heat killed Ogawa cells |
Curator ID | AA + AS |
Date of Curation | 21-06-2011
|
References | 2448333 |