PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 2

Entry No. - 1   [TOP]
PolysacDB ID1764
Carbohydrate NameUnknown carbohydrate   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeMycobacterium paratuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesSoluble cell extracts
Carrier NameNil
Conjugation MethodNil
AntibodiesMab PII-B1
Antibody type and classIgM
Assay SystemELISA, immunoblotting
Cross-reactivityThis Mab cross-reacted with Mycobacterium kansasii and Mycobacterium avium 18
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation24-10-2010
ReferencesPMC174607


Entry No. - 2   [TOP]
PolysacDB ID2613
Carbohydrate NameLipoarabinomannan like polysaccharides   (Drugpedia)
Carbohydrate ClassGlycolipid
MicrobeMycobacterium paratuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cell extract
Carrier NameNil
Conjugation MethodNil
AntibodiesMab PII-B1
Antibody type and classIgM
Assay SystemELISA, ConA lectin Affinity Chromatography
Cross-reactivityThis antibody was cross-reactive to M, tuberculosis, M. kansasii, M.avium
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityUsing this antibody it was for the first time proposed that LaM like poysaccharides were released into the growth medium during mycobacterial growth.
Curator IDAA + AS
Date of Curation19-07-2011
ReferencesPMC174607


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